Acute heart failure and microRNA
نویسندگان
چکیده
منابع مشابه
MicroRNA and Heart Failure.
Heart failure (HF) imposes significant economic and public health burdens upon modern society. It is known that disturbances in neurohormonal status play an important role in the pathogenesis of HF. Therapeutics that antagonize selected neurohormonal pathways, specifically the renin-angiotensin-aldosterone and sympathetic nervous systems, have significantly improved patient outcomes in HF. Neve...
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Acute heart failure (AHF) is a life-threatening emergency, which largely profits from early diagnosis and treatment. The prevalence of AHF is difficult to assess, estimates range between 1 and 12% in the general population. Despite recent therapeutic advances, in-hospital mortality is high with estimates varying from 4 and 18% in different registries. Due to large differences in AHF definitions...
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MicroRNAs (miRNAs) are short, noncoding RNAs that have revolutionized the way we interpret genetic regulation. A component of what was once considered junk DNA, miRNAs regulate virtually every protein-coding gene in a highly dynamic fashion. Growing evidence has indicated that miRNAs are centrally involved in the pathogenesis of heart failure and strategies to modulate their activity therapeuti...
متن کامل[Acute heart failure].
Acute heart failure is always an indication for referral to an intensive care unit. In the widest sense, the term acute heart failure includes the manifestation forms of pulmonary edema, cardiogenic shock or rapid-onset decompensated cardiac insufficiency unaccompanied by shock or pulmonary edema (low-output syndrome). Acute heart failure may occur in the absence of previously known heart disea...
متن کاملAcute Decompensated Heart Failure
eart failure has emerged over the past several decades as a major global public health problem, with rising prevalence reported in both industrialized and developing nations alike.1–6 In addition to the enormous costs in human suffering and loss of productivity, heart failure has imposed an increasingly heavy financial burden on health-care systems throughout the world. Although highly effectiv...
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ژورنال
عنوان ژورنال: Systemic Hypertension
سال: 2019
ISSN: 2542-2189,2075-082X
DOI: 10.26442/2075082x.2019.2.000030